A glass of 100% Orange Juice a day may help keep kidney stones away.
Kidney Stones and Orange Juice
- Stay hydrated – drinking fluids helps dilute the substances that lead to kidney stones. 100% orange juice is ideal for hydration because it contains a high level of water content – 88 percent to be exact.
- Get enough calcium – calcium can bind to food oxalates when consumed together and may reduce the risk of developing one common type of kidney stone.1 Fortified orange juice is an excellent source of calcium and typically contains 350 mg of calcium,2 or about 30% of the recommended Daily Value3* in one 8-ounce glass.
- Avoid too much sodium – excess sodium is associated with calcium loss, and calcium may bind to compounds in urine to form stones.
- Limit animal protein – consuming too much animal protein can lead to high levels of uric acid that may lead to stone formation. Animal proteins also contain phosphates, another factor that may raise the risk of kidney stones.1
- Drink Florida Orange Juice – Florida Orange Juice, along with other citrus beverages, has citrate, which may help prevent kidney stones.
Orange juice is associated with a 12% reduced risk for developing kidney stones.4
Detailed Nutrition Information
Dietary citrate, the usual form of citric acid in solution, is a well-known inhibitor of the formation of calcium oxalate and calcium phosphate stones, as it increases alkalinity of urine (increases pH) and increases citrate excretion.5 Citrus and citrus juices contain both citrate and potassium, which may aid in pH balance of the urine and reduce the risk of calcium loss from the bones.5,6
Multiple reviews, including a meta-analysis, concluded that the consumption of fruit juices, as a source of dietary citrate, can provide alkalization of urine and increase citrate excretion while providing fluid, which in turn reduces the risk of kidney stone formation.5-7 Indeed, researchers have observed the beneficial effects of increased urinary citrate with lemon juice.8-10 Orange juice has also been shown to increase urine pH and citrate and to reduce the supersaturation of calcium oxalate.11 Researchers continue to evaluate orange juice’s role in the prevention of kidney stones.
A prospective analysis of a Japanese cohort found that the consumption of 100% fruit juice was not associated with 5-year changes in kidney function in adults aged 35-69 years.12 High blood levels of uric acid may increase the risk for gout and kidney stones. In a longitudinal analysis of the Brazilian Longitudinal Study of Adult Health, consumption of unsweetened fruit juice was not associated with the incidence of hyperuricemia in adults aged 35-74 years.13 A systematic review and meta-analysis of controlled feeding trials found that 100% fruit juice decreased uric acid levels in certain trials. The certainty of evidence was considered high for the beneficial effect observed with 100% fruit juice.14
Based on the available data, citrus juice, such as 100% orange juice, may be beneficial in some cases to prevent the formation of kidney stones. Patients with mild to moderate hypocitraturia (low citrate in urine) may benefit from the daily intake of citrus based juices as part of a healthy diet. It is best to check with your doctor before making any dietary changes.
*Values based on a 2000 calorie diet. Calculated Daily Value (DV) percentages rounded to nearest whole percent. FDA rounding rules for nutrition labeling not applied when calculating percent DV. Information is not intended for labeling food in packaged form.
- National Institute of Diabetes and Digestive and Kidney Diseases. Eating, Diet and Nutrition for Kidney Stones.
- USDA National Nutrient Database for Standard Reference, Release 28 (slightly revised). US Department of Agriculture, Agricultural Research Service, Nutrient Data Laboratory; May 2016.
- Electronic Code of Federal Regulations. Title 21: Food and Drugs. Part 101 Food Labeling, Subpart A §101.9.
- Ferraro et al. Clin J Am Soc Nephrol. 2013;8:1389-1395.
- Seiner et al. Urolithiasis. 2016;44:51-56.
- Prezioso et al. Archivo Italiano di Urologia e Andrologia. 2015;87(2):105-120.
- Pachaly et al. Nephrol Dial Transplant. 2016;31(8):1203-1211.
- Seltzer et al. J Urology. 1996;156(3):907-909.
- Kang et al. J Urology. 2007;177(4):1358-1362.
- Aras et al. Urol Res. 2008;36:313-317.
- Odvina et al. Clin J Am Soc Nephrol. 2006;1:1269-1274.
- Fujii R et al. Nutrition. 2021;84:111114.
- Siqueira et al. Nutr Metab Cardiovasc Dis. 2021;31(7):2004-2013.
- Ayoub-Charette et al. J Nutr. 2021;151(8):2409-2421.